DIBAC-GGFG-NH2CH2-Dxd

DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a derivative of Camptothecin, serves as a linker-payload for protein-agent conjugates [1]. It is utilized as a payload in the antibody-coupling drug ADC (DS-8201a) . Additionally, this compound functions as a click chemistry reagent due to its DBCO group, facilitating strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-group-containing molecules.

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