Val-Ala-PABC-Exatecan trifluoroacetate
Product Specifications
CAS Number
2928571-45-1
Target
Drug-Linker Conjugates for ADC, Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
Val-Ala-PABC-Exatecan trifluoroacetate is a drug-linker conjugate for antibody-drug conjugates (ADC), comprising a cleavable Tesirine linker, Val-Ala-PABC, and the topoisomerase I inhibitor Exatecan. This compound facilitates the synthesis of ADC molecules, including Mal-PEGn-amide-va-Exatecan [1].
Smiles
C(C(O)=O)(F)(F)F.N(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)C)=O)C=C1)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7
Molecular Formula
C42H44F4N6O10
Molecular Weight
868.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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