HPK1-IN-2 dihydrochloride
Product Specifications
Target
Others|||MAPK|||FLT|||Src
Related Pathways
MAPK|||Others|||Angiogenesis|||Tyrosine Kinase/Adaptors
Bioactivity
HPK1-IN-2 dihydrochloride, a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1) with an IC 50 of less than 0.05 µM, demonstrates significant antitumor activity. It additionally exhibits inhibition of Lck kinase activity, with an IC 50 ranging from 0.05 to less than 0.5 µM, and Flt3 kinase activity, with an IC 50 of less than 0.05 µM [1].
Smiles
NC1=C(C=2NC=3C(N2)=CC=C(C3)N4CCN(C)CC4)C(=O)NC5=C1C=CS5.Cl
Molecular Formula
C19H22Cl2N6OS
Molecular Weight
453.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/187269433570361398/T84714
CAS Number
2375595-72-3
Available Sizes
Curated Selection
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