NPBA

Product Specifications

CAS Number

524033-40-7

Target

Others, Potassium Channel

Related Pathways

Membrane transporter/Ion channel, Others

Bioactivity

NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, concurrently functions as a blocker of the tandem pore domain weak inward rectifying K+ channel (TWIK2) . This compound effectively inhibits NLRP3 inflammasome activation in macrophages [1].

Smiles

N(CCNC(=O)C1=CC=CC=C1)C2=C(C(F)(F)F)C=C(N(=O)=O)C=C2

Molecular Formula

C16H14F3N3O3

Molecular Weight

353.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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