NPBA
Product Specifications
CAS Number
524033-40-7
Target
Others, Potassium Channel
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, concurrently functions as a blocker of the tandem pore domain weak inward rectifying K+ channel (TWIK2) . This compound effectively inhibits NLRP3 inflammasome activation in macrophages [1].
Smiles
N(CCNC(=O)C1=CC=CC=C1)C2=C(C(F)(F)F)C=C(N(=O)=O)C=C2
Molecular Formula
C16H14F3N3O3
Molecular Weight
353.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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