9-keto Fluprostenol isopropyl ester
Product Specifications
CAS Number
1219032-18-4
Target
Others|||Prostaglandin Receptor
Related Pathways
Immunology/Inflammation|||Others|||GPCR/G Protein
Bioactivity
9-Keto Fluprostenol Isopropyl Ester, an ester derivative of the FP receptor agonist fluprostenol, undergoes oxidation at carbon 9. This compound serves as a potential prodrug for 9-keto fluprostenol, which may function as an agonist at EP receptors. Additionally, it is considered a possible metabolite of fluprostenol isopropyl ester (travoprost), drawing parallels to the metabolism of latanoprost by 15-hydroxyprostaglandin dehydrogenase observed in monkey cornea. Furthermore, certain F-series prostaglandins, such as 6-keto prostaglandin F1? (PGF1?), undergo conversion to their E-series counterparts in isolated human platelets, highlighting a metabolic pathway of relevance.
Smiles
C(/C=C\CCCC(OC(C)C)=O)[C@@H]1[C@@H](/C=C/[C@H](COC2=CC(C(F)(F)F)=CC=C2)O)[C@H](O)CC1=O
Molecular Formula
C26H33F3O6
Molecular Weight
498.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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