Dihomo-γ-Linolenic Acid ethyl ester

Ethyl dihomo-?-linolenic acid ethyl ester (ethyl DGLA), an ?-6 fatty acid intermediate ester form, elevates prostaglandin E1 (PGE1) and PGE2 secretion in rabbit renal papilla when administered dietarily at a dosage of 1 g/kg per day for 25 days. Additionally, this dosage of ethyl DGLA increases triglyceride levels and enhances the proportion of 20:3?6 and 20:4?6 phospholipids in the renal medulla of rabbits. Ethyl DGLA formulations have been employed in managing eczema and inflammatory disorders.