17-phenyl trinor Prostaglandin E2
Product Specifications
CAS Number
38315-43-4
Target
Others, Prostaglandin Receptor
Related Pathways
Others, Immunology/Inflammation, GPCR/G Protein
Bioactivity
17-Phenyl trinor Prostaglandin E2 (17-phenyl trinor PGE2) is a synthetic analog of PGE2, functioning as an agonist at the EP1 and EP3 receptors. It induces contraction of the guinea pig ileum at a 11 μM concentration and displays slightly less potency than PGE2 in stimulating the gerbil colon and rat uterus. Notably, with an ED50 value of 350 μg/kg, 17-phenyl trinor PGE2 exhibits 4.4 times greater antifertility efficacy in hamsters compared to PGE2.
Smiles
C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCC2=CC=CC=C2)O)[C@H](O)CC1=O
Molecular Formula
C23H30O5
Molecular Weight
386.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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