11-deoxy-16,16-dimethyl Prostaglandin E2
Product Specifications
CAS Number
53658-98-3
Target
Others, Prostaglandin Receptor
Related Pathways
GPCR/G Protein, Others, Immunology/Inflammation
Bioactivity
11-Deoxy-16,16-dimethyl Prostaglandin E2 (11-deoxy-16,16-dimethyl PGE2) is a stable synthetic analog of Prostaglandin E2 (PGE2), acting as an agonist for both EP2 and EP3 receptors. It effectively inhibits gastric acid secretion and ulcer formation in rats, with ED50 values of 1 mg/kg and 0.021 mg/kg, respectively. This compound is also 900 times more potent than Prostaglandin F2α (PGF2α) in inducing contraction of human respiratory tract smooth muscle in vitro.
Smiles
CCCCC(C)(C)[C@H](O)\C=C\[C@H]1CCC(=O)[C@@H]1C\C=C/CCCC(O)=O
Molecular Formula
C22H36O4
Molecular Weight
364.526
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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