What is the catalog number for U-51605?

The catalog number for U-51605 is T84575.

What sizes are available for U-51605?

U-51605 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does U-51605 come in?

U-51605 is available in 2 different pack sizes.

U-51605 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures U-51605?

U-51605 is manufactured by Molfinity.

What is the estimated delivery time for U-51605?

Estimated delivery time for U-51605 is approximately 10 business day(s), depending on your location.

U-51605

Product Specifications

CAS Number

64192-56-9

Target

PGE Synthase, Others

Related Pathways

Immunology/Inflammation, Others

Bioactivity

U-51605, a stable analog of the endoperoxide prostaglandin H2 (PGH2), functions as an inhibitor with greater selectivity towards prostacyclin (PGI) synthase over thromboxane (TX) synthase. It also acts as a partial agonist at TP receptors. Studies show that at a concentration of 2.8 μM, U-51605 effectively inhibits PGI synthase in human foreskin fibroblasts, while a concentration of 5.6 μM is required to inhibit human platelet TX synthase. Furthermore, U-51605, at up to 1 μM, decreases the release of prostacyclin in SHR aorta triggered by the calcium ionophore A-23187 without impacting TXA2 production, and notably enhances the release of PGE2 and PGF2α.