ROCK-IN-10
Product Specifications
CAS Number
1038549-25-5
Target
Others, ROCK
Related Pathways
Stem Cells, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Others
Bioactivity
ROCK-IN-10 (compound 50) serves as a powerful inhibitor of ROCK, exhibiting IC50 values of 6 nM for ROCK1 and 4 nM for ROCK2, respectively. It demonstrates over 100-fold selectivity towards ROCK1 and ROCK2 when compared to other kinases [1].
Smiles
NC(=O)c1ccc(NC(=O)NCc2cccc(c2)C(=O)Nc2ccc3CCNCc3c2)cc1
Molecular Formula
C25H25N5O3
Molecular Weight
443.507
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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