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ROCK-IN-10

Product Specifications

CAS Number

1038549-25-5

Target

Others, ROCK

Related Pathways

Stem Cells, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Others

Bioactivity

ROCK-IN-10 (compound 50) serves as a powerful inhibitor of ROCK, exhibiting IC50 values of 6 nM for ROCK1 and 4 nM for ROCK2, respectively. It demonstrates over 100-fold selectivity towards ROCK1 and ROCK2 when compared to other kinases [1].

Smiles

NC(=O)c1ccc(NC(=O)NCc2cccc(c2)C(=O)Nc2ccc3CCNCc3c2)cc1

Molecular Formula

C25H25N5O3

Molecular Weight

443.507

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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