Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

LY303511 hydrochloride

Product Specifications

CAS Number

854127-90-5

Target

Others, Potassium Channel, TNF

Related Pathways

Apoptosis, Membrane transporter/Ion channel, Others

Bioactivity

LY303511, a structural analog of LY294002, selectively inhibits mTOR-dependent phosphorylation of S6K, unlike its counterpart, which acts as a phosphatidylinositol 3-kinase (PI3K) inhibitor. It effectively reduces cell proliferation in human lung epithelial adenocarcinoma cells by hindering G2/M phase progression and suppressing casein kinase 2 activity. Additionally, LY303511 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sensitivity in HeLa cells resistant to TRAIL-induced apoptosis and blocks voltage-gated potassium (Kv) channels.

Smiles

Cl.Cl.O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCNCC1

Molecular Formula

C19H20Cl2N2O2

Molecular Weight

379.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Eukaryotic translation initiation factor 1b (EIF1B) ELISA Kit
GTR10317365 96 Well

Rabbit Eukaryotic translation initiation factor 1b (EIF1B) ELISA Kit

Sign In for Pricing
View Details
Polyclonal Antibody to Angiopoietin 1 (ANGPT1)
TRV-0003507-01 20 µL

Polyclonal Antibody to Angiopoietin 1 (ANGPT1)

Sign In for Pricing
View Details
Polyclonal Antibody to Angiopoietin 1 (ANGPT1)
TRV-0003507-02 100 µL

Polyclonal Antibody to Angiopoietin 1 (ANGPT1)

Sign In for Pricing
View Details
Polyclonal Antibody to Angiopoietin 1 (ANGPT1)
TRV-0003507-03 200 µL

Polyclonal Antibody to Angiopoietin 1 (ANGPT1)

Sign In for Pricing
View Details
Polyclonal Antibody to Angiopoietin 1 (ANGPT1)
TRV-0003507-04 1 mL

Polyclonal Antibody to Angiopoietin 1 (ANGPT1)

Sign In for Pricing
View Details
Porcine AGC (Aggrecan) ELISA Kit
EP22606 96 Tests

Porcine AGC (Aggrecan) ELISA Kit

Sign In for Pricing
View Details