WJ-39
Product Specifications
CAS Number
3009908-95-3
Target
Mitophagy, Reductase, Apoptosis, Mitochondrial Metabolism
Related Pathways
Autophagy, Endocrinology/Hormones, Apoptosis, Metabolism
Purity
0.9945
Bioactivity
WJ-39 is an orally active aldose reductase (AR) inhibitor that ameliorates renal lesions in diabetic nephropathy through activation of Nrf2 signaling, and may be used to ameliorate renal insufficiency and fibrosis.WJ-39 inhibits oxidative stress and inhibits the activation of the inflammatory vesicle of the oligomerization structural domain-like receptor family, pyrin structural domain 3 (NLRP3) .
Smiles
O=C(CN1C=C(CC2=C(Cl)C(Cl)=CC=C2)C(C3=CC(OC)=CC=C31)=O)[O-].[K+]
Molecular Formula
C19H14Cl2KNO4
Molecular Weight
430.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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