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DC 432

Product Specifications

CAS Number

2388988-70-1

Target

Others

Related Pathways

Others

Bioactivity

DC 432, a potent peptidomimetic inhibitor of N-terminal methyltransferase 1/2 (NTMT1/2) with an IC50 value of 54 nM, incorporates a BM30 peptide enhanced by five arginine residues. It effectively reduces the N-terminal methylation level of the regulator of chromosome condensation 1 and SET proteins in HCT116 cells, demonstrating cell permeability.

Smiles

O=C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)[C@@H]1N(C(CC2=CC=C(O)C=C2)=O)CCC1

Molecular Formula

C55H100N28O10

Molecular Weight

1313.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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