JQ1-FITC
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
JQ1-FITC, a fluorescent BET bromodomain probe, exhibits high affinity binding to BRD4 (BD1) and BRD4 (BD2), with KD, app values of 6.5 nM and 5.8 nM respectively, as determined using GST-tagged BRD4 proteins in a CoraFluorTR-FRET assay; for BRD4 (BD1), the value is 58.7 nM in a fluorescence anisotropy assay. It has excitation and emission maxima (λ) of 495 nm and 525 nm.
Smiles
O=C(NCCCOCCOCCOCCCNC(NC1=CC=C(C(C(O)=O)=C1)C2=C(C(OC3=C2C=CC(O)=C3)=C4)C=CC4=O)=S)C[C@@H]5N=C(C6=CC=C(Cl)C=C6)C7=C(SC(C)=C7C)N8C5=NN=C8C.OC(C(F)(F)F)=O
Molecular Formula
C50H50ClN7O9S2.CF3CO2H
Molecular Weight
1106.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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