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IMCTA-C14 TFA

Product Specifications

Target

Others, Autophagy, Antibacterial

Related Pathways

Others, Microbiology/Virology, Autophagy

Bioactivity

IMCTA-C14, a detergent and derivative of the microbial metabolite 4-trehalosamine, exhibits a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. It effectively extracts proteins, including membrane proteins, from OVK18 ovarian cancer cells at concentrations of 0.05 and 0.5%. Furthermore, IMCTA-C14 demonstrates antibacterial activity against various bacterial strains (MICs = 8-128 μg/ml) and shows cytotoxicity against a spectrum of 52 cancer cell lines (IC50s = 2.9-29.2 μg/ml) . At a concentration of 50 μM, it induces autophagy in OVK18 cells.

Smiles

OC(C(F)(F)F)=O.O[C@@H]([C@@H]([C@H](O1)CO)NCCCCCCCCCCCCCC)[C@@H](O)[C@H]1O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO

Molecular Formula

C26H51NO10.CF3COOH

Molecular Weight

651.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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