What is the catalog number for Sulfonadyn-47?

The catalog number for Sulfonadyn-47 is T83891.

What sizes are available for Sulfonadyn-47?

Sulfonadyn-47 is available in the following size(s): 500 µg, 1 mg, 5 mg, 10 mg.

How many pack sizes does Sulfonadyn-47 come in?

Sulfonadyn-47 is available in 4 different pack sizes.

Is Sulfonadyn-47 in stock?

Sulfonadyn-47 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Sulfonadyn-47?

Sulfonadyn-47 is manufactured by Molfinity.

What is the estimated delivery time for Sulfonadyn-47?

Estimated delivery time for Sulfonadyn-47 is approximately 10 business day(s), depending on your location.

Sulfonadyn-47

Product Specifications

Target

Others

Related Pathways

Others

Bioactivity

Sulfonadyn-47 is a dynamin inhibitor that effectively inhibits dynamin GTPase activity with an IC50 of 3.5 μM in cell-free assays. Additionally, it disrupts clathrin-mediated endocytosis in U2OS cells (IC50 = 27.3 μM) and impedes the depolarization-stimulated uptake of the synaptic vesicle endocytosis (SVE) marker FM4-64 in isolated rat brain synaptosomes (IC50 = 12.3 μM) . Significantly, in vivo administration of sulfonadyn-47 at doses of 30 and 60 mg/kg demonstrates anticonvulsant properties in the 6 Hz corneal kindling mouse model of seizures.