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4- (3,4-Difluorobenzo) curcumin

Product Specifications

CAS Number

1170354-22-9

Target

Others, ROS

Related Pathways

Immunology/Inflammation, Others

Bioactivity

4- (3,4-Difluorobenzo) curcumin (CDF) is a semisynthetic coumarin noted for its antiparasitic and anticancer properties. It effectively reduces the population of Vero cells infected by T. gondii promastigotes and amastigotes, with EC50 values of 0.8 and 0.37 μM, respectively. Furthermore, at concentrations of 4 and 8 μM, CDF enhances the efficacy of 5-fluorouracil and oxaliplatin in inhibiting the formation of both primary and secondary colonospheres in chemoresistant HCT116 cells.

Smiles

FC(C=C1/C=C(C(/C=C/C2=CC(OC)=C(C=C2)O)=O)/C(/C=C/C3=CC(OC)=C(C=C3)O)=O)=C(C=C1)F

Molecular Formula

C28H22F2O6

Molecular Weight

492.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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