4- (3,4-Difluorobenzo) curcumin
Product Specifications
CAS Number
1170354-22-9
Target
Others, ROS
Related Pathways
Immunology/Inflammation, Others
Bioactivity
4- (3,4-Difluorobenzo) curcumin (CDF) is a semisynthetic coumarin noted for its antiparasitic and anticancer properties. It effectively reduces the population of Vero cells infected by T. gondii promastigotes and amastigotes, with EC50 values of 0.8 and 0.37 μM, respectively. Furthermore, at concentrations of 4 and 8 μM, CDF enhances the efficacy of 5-fluorouracil and oxaliplatin in inhibiting the formation of both primary and secondary colonospheres in chemoresistant HCT116 cells.
Smiles
FC(C=C1/C=C(C(/C=C/C2=CC(OC)=C(C=C2)O)=O)/C(/C=C/C3=CC(OC)=C(C=C3)O)=O)=C(C=C1)F
Molecular Formula
C28H22F2O6
Molecular Weight
492.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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