Dabigatran Acyl-β-D-Glucuronide TFA
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
Dabigatran acyl-β-D-glucuronide, an active metabolite of the thrombin inhibitor dabigatran, is synthesized predominantly through the action of the UDP-glucuronosyltransferase isoform UGT2B15. This compound, at a concentration of 0.46 μM, effectively prolongs activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma.
Smiles
CN1C2=CC=C(C(N(CCC(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)=O)C4=NC=CC=C4)=O)C=C2N=C1CNC5=CC=C(C(N)=N)C=C5.OC(C(F)(F)F)=O
Molecular Formula
C31H33N7O9.XCF3COOH
Molecular Weight
647.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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