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(±) 13,14-EDT

Product Specifications

CAS Number

355016-19-2

Target

Drug Metabolite, Others

Related Pathways

Metabolism, Others

Bioactivity

(±) 13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat coronary small arterial smooth muscle cells at 50 nM, promoting dilation. Additionally, it induces arteriole dilation in isolated porcine samples with an EC50 of 12 pM and relaxes isolated bovine coronary arteries previously contracted by TP receptor agonist U-46619.

Smiles

OC(CCCCC/C=C\C/C=C\C[C@@H]1[C@@H](O1)C/C=C\CCCCC)=O

Molecular Formula

C22H36O3

Molecular Weight

348.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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