Uridine-5'-O- (3-thiotriphosphate) sodium
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
Uridine-5'-O- (3-thiotriphosphate) (UTP-γ-S) is a hydrolysis-resistant UTP derivative and an agonist of the purinergic P2Y2 receptor. It effectively induces inositol phosphate formation in 1321N1 astrocytoma cells harboring the human P2Y2 receptor (EC50 = 240 nM) and stimulates chloride secretion in a dose-dependent manner in primary nasal epithelial cells from cystic fibrosis patients. Moreover, UTP-γ-S prompts vasoconstriction in isolated human coronary arteries (EC50 = 25.1 μM) .
Smiles
[S-]P([O-])(OP([O-])(OP([O-])(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)N2C=CC(NC2=O)=O)=O)=O)=O.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C9H11N2O14P3S.4Na
Molecular Weight
588.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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