ATP-γ-S tetrasodium
Product Specifications
CAS Number
88453-52-5
Target
P2Y Receptor, PERK
Related Pathways
Neuroscience, Apoptosis, GPCR/G Protein
Bioactivity
ATP-γ-S tetrasodium (Adenosine-5'-O- (3-thiotriphosphate) tetrasodium) is a purinergic P2Y11 receptor agonist and ATP analog that induces inositol phosphate accumulation, induces insulin secretion from MIN6 pancreatic islet β-cells, and induces an increase in intracellular calcium concentration. ATP-γ-S tetrasodium inhibits the induction of the Junin virus. Junin virus-induced increase in the level of mRNA encoding bone morphogenetic protein 6 (BMP6) reduces particle-forming units (PFUs) in Junin virus-infected primary rat osteoblasts.
Smiles
O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([S-])=O)([O-])=O)([O-])=O)N2C3=NC=NC(N)=C3N=C2.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C10H12N5Na4O12P3S
Molecular Weight
611.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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