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8-Bromoguanosine-5'-O-triphosphate sodium

Product Specifications

Target

Others

Related Pathways

Others

Bioactivity

8-Bromoguanosine-5'-O-triphosphate, a derivative of guanosine 5'-triphosphate (GTP) - the energy substrate for protein synthesis and gluconeogenesis, acts as an inhibitor of the E. coli GTPase FtsZ with an inhibition constant (Ki) of 31.8 µM. Furthermore, at a concentration of 500 µM, it facilitates the assembly of porcine brain microtubules in a cell-free assay.

Smiles

O[C@@H]1[C@H](O)[C@@H](COP([O-])(OP(OP([O-])([O-])=O)([O-])=O)=O)O[C@H]1N2C(Br)=NC3=C2NC(N)=NC3=O.[Na+].[Na+].[Na+].[Na+]

Molecular Formula

C10H11BrN5O14P3.4Na

Molecular Weight

690

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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