8-Bromoguanosine-5'-O-triphosphate sodium
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
8-Bromoguanosine-5'-O-triphosphate, a derivative of guanosine 5'-triphosphate (GTP) - the energy substrate for protein synthesis and gluconeogenesis, acts as an inhibitor of the E. coli GTPase FtsZ with an inhibition constant (Ki) of 31.8 µM. Furthermore, at a concentration of 500 µM, it facilitates the assembly of porcine brain microtubules in a cell-free assay.
Smiles
O[C@@H]1[C@H](O)[C@@H](COP([O-])(OP(OP([O-])([O-])=O)([O-])=O)=O)O[C@H]1N2C(Br)=NC3=C2NC(N)=NC3=O.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C10H11BrN5O14P3.4Na
Molecular Weight
690
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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