Sp-Adenosine-5'-O- (1-thiodiphosphate) sodium
Product Specifications
CAS Number
2005478-90-8
Target
Others
Related Pathways
Others
Bioactivity
Sp-Adenosine-5'-O- (1-thiodiphosphate) (Sp-ADP-α-S), an isomer of the sulfur-containing nucleotide derivative ADP-α-S, functions as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 μM. This compound also promotes aggregation of isolated human platelets with an effective concentration (EC50) of 20 μM and induces relaxation in carbamoylcholine-precontracted guinea pig taenia coli with an EC50 of 58.9 μM.
Smiles
O[C@@H]1[C@@H](CO[P@@](OP([O-])([O-])=O)([S-])=O)O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]1O.[Na+].[Na+].[Na+]
Molecular Formula
C10H12N5O9P2S.3Na
Molecular Weight
509.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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