Rp-Adenosine-5'-O- (1-thiodiphosphate) sodium
Product Specifications
CAS Number
2005478-89-5
Target
Others
Related Pathways
Others
Bioactivity
Rp-Adenosine-5'-O- (1-thiodiphosphate) (Rp-ADP-?-S), a sulfur-containing isomer of the nucleotide derivative ADP-?-S, acts as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 µM. This compound also induces aggregation in isolated human platelets with an effective concentration (EC50) of 20 µM and promotes relaxation in guinea pig taenia coli that has been precontracted with carbamoylcholine, with an EC50 of 58.9 µM.
Smiles
O[C@@H]1[C@@H](CO[P@](OP([O-])([O-])=O)([S-])=O)O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]1O.[Na+].[Na+].[Na+]
Molecular Formula
C10H12N5O9P2S.3Na
Molecular Weight
509.21
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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