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SsK36 TFA

Product Specifications

Target

Others

Related Pathways

Others

Bioactivity

SsK36, a peptide super-substrate for the histone methyltransferase SET domain-containing protein 2 (SETD2), is derived from histone H3 lysine 36 (H3K36) amino acids 29-43, with modifications at positions 31, 32, 36, 37, and 39. It undergoes methylation at a rate 70 times greater and 290 times faster than the unmodified H3K36 (29-43) in cell-free assays.

Smiles

[H]N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(NCC(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N2CCC[C@H]2C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N3CCC[C@H]3C(O)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)C.OC(C(F)(F)F)=O

Molecular Formula

C79H127N29O18.XCF3COOH

Molecular Weight

1771.1

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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