Cys-Pexiganan TFA

Cys-pexiganan, a derivative of pexiganan with an added N-terminal cysteine, is an antimicrobial peptide effective against P. aeruginosa and S. aureus, with minimum inhibitory concentrations (MICs) of 64 and 16 µg/ml, respectively. Its conjugation to cellulose acetate-incorporated polyvinyl alcohol electrospun mats enhances the clotting of isolated recalcified human plasma.

O=C([C@@H](N)CS)NCC(N[C@@]([H])([C@H](CC)C)C(NCC(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(NCC(N[C@H](C(N[C@@H](C)C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@@]([H])([C@H](CC)C)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CCCCN)=O)=O)=O)CCCCN)=O)C(C)C)=O)=O)=O)CCCCN)=O)=O)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)CCCCN)=O)=O)=O)CCCCN)=O)=O)=O.OC(C(F)(F)F)=O