Mca-SEVNLDAEFR-K (Dnp) -RR-NH2 acetate

Mca-SEVNLDAEFR-K (Dnp) -RR-NH2 is a fluorogenic substrate designed for the quantification of ?-secretase (BACE) activity. When cleaved by BACE, it liberates 7-methoxycoumarin-4-acetyl (Mca), a compound whose fluorescence, with excitation and emission peaks at 328 nm and 420 nm respectively, serves as a measurable indicator of BACE enzymatic action.

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