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YS-67

Product Specifications

CAS Number

2761327-15-3

Target

EGFR, Akt, Apoptosis

Related Pathways

JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Apoptosis, PI3K/Akt/mTOR signaling

Purity

0.9888

Bioactivity

YS-67 is an orally available, selective and potent EGFR inhibitor with antitumor activity, inhibits p-EGFR and p-AKT, and inhibits the proliferation of A549, PC-9, and A431 cells.YS-67 blocks cell cycle progression and induces apoptosis in the G0/G1 phase, and can be used in the study of non-small-cell lung cancer.

Smiles

N=1C=NC(=C2C=C(OCCCN3CCOCC3)C(OC)=CC12)C=4C=5C=CC=CC5N(C4C=6C=CC=CC6)CC

Molecular Formula

C32H34N4O3

Molecular Weight

522.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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