YS-67
Product Specifications
CAS Number
2761327-15-3
Target
EGFR|||Akt|||Apoptosis
Related Pathways
JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Apoptosis|||PI3K/Akt/mTOR signaling
Purity
0.9888
Bioactivity
YS-67 is an orally available, selective and potent EGFR inhibitor with antitumor activity, inhibits p-EGFR and p-AKT, and inhibits the proliferation of A549, PC-9, and A431 cells.YS-67 blocks cell cycle progression and induces apoptosis in the G0/G1 phase, and can be used in the study of non-small-cell lung cancer.
Smiles
N=1C=NC(=C2C=C(OCCCN3CCOCC3)C(OC)=CC12)C=4C=5C=CC=CC5N(C4C=6C=CC=CC6)CC
Molecular Formula
C32H34N4O3
Molecular Weight
522.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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