12R-LOX-IN-1
Product Specifications
CAS Number
857758-13-5
Target
Others|||DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Others
Bioactivity
12R-LOX-IN-1 (Compound 4a), with an IC50 of 28.25 µM, is an inhibitor of 12R-LOX. It suppresses hyperproliferation and colony formation in Imiquimod-induced psoriatic keratinocytes, and reduces levels of reactive oxygen species, Ki67, IL-17A, TNF-?, and IL-6. This compound has utility in antipsoriatic research [1].
Smiles
OC=1C=CC=2N=C(C=CC2C1)C=3C=CC=CC3O
Molecular Formula
C15H11NO2
Molecular Weight
237.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
P3282-04C 400 µg
Peptide Histidine Isoleucinamide 27 (Intestinal Peptide PHI-27, PHI27, PHI-27)
Ask
View Details ![Mouse Monoclonal SNW1 Antibody (PCRP-SNW1-1C12) [mFluor Violet 610 SE]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP3-26930MFV610 0.1 mL
Mouse Monoclonal SNW1 Antibody (PCRP-SNW1-1C12) [mFluor Violet 610 SE]
Ask
View Details 