A3373
Product Specifications
Target
Phospholipase
Related Pathways
Metabolism
Bioactivity
A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) of 325 nM for PLD1 and 15.15?M for PLD2. This compound effectively suppresses lipopolysaccharide (LPS) -induced immune responses and is implicated in key processes of autoimmune arthritis, bone demineralization, and osteoclastogenesis [1] [2].
Smiles
O=C(NC=1C=C(C=C(C1)C(F)(F)F)C(F)(F)F)C2=CC=3C=C(F)C=CC3N2
Molecular Formula
C17H9F7N2O
Molecular Weight
390.26
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/132882557011230755/T83226
CAS Number
2324948-66-3
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1398395-01 0.02 mg (E-Coli)
Recombinant Gloeobacter violaceus Heat-inducible transcription repressor HrcA (hrcA)
Ask
View Details 
MBS1398395-02 0.02 mg (Yeast)
Recombinant Gloeobacter violaceus Heat-inducible transcription repressor HrcA (hrcA)
Ask
View Details 
MBS1398395-03 0.1 mg (E-Coli)
Recombinant Gloeobacter violaceus Heat-inducible transcription repressor HrcA (hrcA)
Ask
View Details MBS1398395-04 0.1 mg (Yeast)
Recombinant Gloeobacter violaceus Heat-inducible transcription repressor HrcA (hrcA)
Ask
View Details MBS1398395-05 0.02 mg (Baculovirus)
Recombinant Gloeobacter violaceus Heat-inducible transcription repressor HrcA (hrcA)
Ask
View Details MBS1398395-06 0.02 mg (Mammalian-Cell)
Recombinant Gloeobacter violaceus Heat-inducible transcription repressor HrcA (hrcA)
Ask
View Details