TM11
TM11, a Tanshinone mimic, is a potent HuR inhibitor that can inhibit HuR-RNA complex formation. TM11 reduces LPS-induced inflammatory response in murine macrophages[1].
Product Specifications
UNSPSC
12352005
Target
HuR
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tm11.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N(S(=O)(C3=CC=CC=C3)=O)C=C2C4=CC=CO4)C=CC1=O
Molecular Formula
C18H11NO5S
Molecular Weight
353.35
References & Citations
[1]Facen E, et, al. Novel, soluble 3-heteroaryl-substituted tanshinone mimics attenuate the inflammatory response in murine macrophages. Sci Rep. 2024 Oct 18;14 (1) :24501.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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