TM11
TM11, a Tanshinone mimic, is a potent HuR inhibitor that can inhibit HuR-RNA complex formation. TM11 reduces LPS-induced inflammatory response in murine macrophages[1].
Product Specifications
UNSPSC
12352005
Target
HuR
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tm11.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N(S(=O)(C3=CC=CC=C3)=O)C=C2C4=CC=CO4)C=CC1=O
Molecular Formula
C18H11NO5S
Molecular Weight
353.35
References & Citations
[1]Facen E, et, al. Novel, soluble 3-heteroaryl-substituted tanshinone mimics attenuate the inflammatory response in murine macrophages. Sci Rep. 2024 Oct 18;14 (1) :24501.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
043092-APC 200 µL
TNIP2, ID (TNIP2, ABIN2, FLIP1, TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, Fetal liver LKB1-interacting protein) (APC) discontinued
Sign In for Pricing
View Details EK343102 96 Well
Mouse TBG (Thyroxine Binding Globulin) ValidElisa Kit
Sign In for Pricing
View Details 
RC220326L3 10 µg
Eph receptor A3 (EPHA3) (NM_182644) Human Tagged Lenti ORF Clone
Sign In for Pricing
View Details 
GTR10390907 96 Well
Monkey Cytosolic phospholipase A2 gamma (PLA2G4C) ELISA kit
Sign In for Pricing
View Details