Amyloid β-Protein (3-42)

Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified to pyroglutamate Aβ (pEAβ) (3-42) . This modified form, pEAβ (3-42), hastens the aggregation of Aβ (1-42) although Aβ (1-42) markedly decelerates both the primary and secondary nucleation of pEAβ (3-42) [1].