Antitumor agent-67
Product Specifications
CAS Number
2820146-10-7
Target
Microtubule Associated, Others
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
Antitumor agent-67 (compound 3), a potent antitumor agent, exhibits highly selective toxicity toward cancer cells while sparing normal cells. This compound can be activated by NQO1 to effectively release podophyllotoxin, thereby killing tumor cells. In HepG2 xenograft models, Antitumor agent-67 significantly inhibits cancer growth with minimal toxicity [1].
Smiles
O=C1[C@@]2([C@@H](C=3C([C@@H](OC(OCC4=CC=C(N(C(CC(C)(C)C5=C(C)C(=O)C(C)=C(C)C5=O)=O)C)C=C4)=O)[C@]2(CO1)[H])=CC6=C(C3)OCO6)C7=CC(OC)=C(OC)C(OC)=C7)[H]
Molecular Formula
C45H47NO13
Molecular Weight
809.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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