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AP-C6

Product Specifications

CAS Number

2234276-60-7

Target

PKA, Others

Related Pathways

Tyrosine Kinase/Adaptors, Others

Bioactivity

AP-C6 is a potent inhibitor of guanosine 3',5'-cyclic monophosphate (cGMP) -dependent protein kinase II (cGKII), with a pIC50 of 6.5. It inhibits human cGKII activity in vitro in a concentration-dependent manner and potentiates cAMP signaling through phosphodiesterase (PDE) inhibition [1].

Smiles

OCCNC1=NC=CC(=N1)C=2C=CC(=CC2)N3C=NC=C3

Molecular Formula

C15H15N5O

Molecular Weight

281.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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