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BChE-IN-20

Product Specifications

CAS Number

1428439-79-5

Target

Cholinesterase (ChE) |||Others

Related Pathways

Neuroscience|||Others

Bioactivity

BChE-IN-20 (compound 7c) is a potent and selective inhibitor of BChE, with IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE. It also inhibits P glycoprotein with an IC50 of 0.27 ?M. BChE-IN-20 serves as a promising template for the design and development of pharmaceutical BChE-selective ligands, including inhibitors and fluorogenic probes.

Smiles

O=C(OC)C1=CN(CCC=2N=C(N=C(NCCCN(CC)CC)C2C1)C=3C=CC=CC3)C(C)C

Molecular Formula

C27H39N5O2

Molecular Weight

465.63

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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