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Bemfivastatin hemicalcium

Product Specifications

CAS Number

805241-64-9

Target

Others, HMG-CoA Reductase

Related Pathways

Metabolism, Others

Bioactivity

Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent. It amplifies liver extract activity and exhibits no-observed adverse effect levels (NOAEL) at dosages of ≥320 mg/kg/d for rat developmental toxicity, ≥12.5 mg/kg/d for rabbit maternal toxicity, and ≥25 mg/kg/d for rabbit developmental toxicity. This compound is utilized in research concerning hypercholesterolemic myalgia in patients intolerant to statins.

Smiles

[O-]C(C[C@H](O)C[C@H](O)CCN1C(C2=CC=C(C=C2)F)=C(C3=CC=CC=C3)C(C(NC4=CC=C(C=C4)CO)=O)=C1C(C)C)=O.[Ca+2]

Molecular Formula

C34H36FN2O6.1/2Ca

Molecular Weight

607.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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