C5aR1 antagonist peptide
Product Specifications
CAS Number
230968-98-6
Bioactivity
C5aR1 antagonist peptide, a biologically active linear peptide originating from the C-terminus of the chemokine complement fragment 5 anaphylatoxin (C5a), inhibits C5a binding and activity at human and rat C5a receptors. Overexpression of C5a is linked to various immunoinflammatory diseases, including arthritis, Alzheimer's disease, cystic fibrosis, and systemic lupus erythematosus.
Smiles
C([C@H](NC([C@@H](CC1CCCCC1)NC(=O)[C@H]2N(C([C@@H](NC([C@H](CC3=CC=CC=C3)N)=O)CCCCN)=O)CCC2)=O)C(N[C@H](CCCNC(=N)N)C(O)=O)=O)C=4C=5C(NC4)=CC=CC5
Molecular Formula
C46H67N11O7
Molecular Weight
886.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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