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C5aR1 antagonist peptide

Product Specifications

CAS Number

230968-98-6

Bioactivity

C5aR1 antagonist peptide, a biologically active linear peptide originating from the C-terminus of the chemokine complement fragment 5 anaphylatoxin (C5a), inhibits C5a binding and activity at human and rat C5a receptors. Overexpression of C5a is linked to various immunoinflammatory diseases, including arthritis, Alzheimer's disease, cystic fibrosis, and systemic lupus erythematosus.

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C([C@H](NC([C@@H](CC1CCCCC1)NC(=O)[C@H]2N(C([C@@H](NC([C@H](CC3=CC=CC=C3)N)=O)CCCCN)=O)CCC2)=O)C(N[C@H](CCCNC(=N)N)C(O)=O)=O)C=4C=5C(NC4)=CC=CC5

Molecular Formula

C46H67N11O7

Molecular Weight

886.09

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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