Cisd2 agonist 2
Product Specifications
CAS Number
2916371-59-8
Target
Others, IKZF
Related Pathways
Others, Immunology/Inflammation
Bioactivity
Cisd2 agonist 2 (compound 6), with an EC50 of 191 nM, is an orally active activator of Cisd2, a protein whose levels are associated with nonalcoholic fatty liver disease (NAFLD) . In vivo studies have demonstrated that Cisd2 agonist 2 exhibits no significant toxicity in heterozygous hepatocyte-specific Cisd2 knockout (Cisd2hKO-het) mice [1].
Smiles
O=C(OC)C1=C(SC(C(=O)NC2=CC=C(O)C=C2)=C1C)N
Molecular Formula
C14H14N2O4S
Molecular Weight
306.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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