DA-PROTAC
Product Specifications
CAS Number
2488660-12-2
Target
PROTACs, Ligand for E3 Ligase
Related Pathways
PROTAC
Bioactivity
DA-PROTAC is a potent degrader of the copper ion-transport proteins Atox1 and CCS, capable of binding to both proteins and facilitating their association with E3 ligase. This interaction enhances the ubiquitination and subsequent proteasomal degradation of Atox1 and CCS. DA-PROTAC is utilized in triple negative breast cancer research [1].
Smiles
N(C(COCCCOCC(NC(C(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1)C(C)(C)C)=O)=O)C=4C5=C(SC4C(NC6=C(Br)C=C(F)C=C6F)=O)N=C7C(=C5)CCC7
Molecular Formula
C46H50BrF2N7O8S2
Molecular Weight
1010.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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