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DA-PROTAC

Product Specifications

CAS Number

2488660-12-2

Target

PROTACs, Ligand for E3 Ligase

Related Pathways

PROTAC

Bioactivity

DA-PROTAC is a potent degrader of the copper ion-transport proteins Atox1 and CCS, capable of binding to both proteins and facilitating their association with E3 ligase. This interaction enhances the ubiquitination and subsequent proteasomal degradation of Atox1 and CCS. DA-PROTAC is utilized in triple negative breast cancer research [1].

Smiles

N(C(COCCCOCC(NC(C(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1)C(C)(C)C)=O)=O)C=4C5=C(SC4C(NC6=C(Br)C=C(F)C=C6F)=O)N=C7C(=C5)CCC7

Molecular Formula

C46H50BrF2N7O8S2

Molecular Weight

1010.96

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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