Dargistotug
Product Specifications
CAS Number
2649362-29-6
Target
Immunology/Inflammation related
Related Pathways
Immunology/Inflammation
Purity
0.985
Bioactivity
Dargistotug (M-6223), a fully human IgG1 monoclonal antibody, specifically binds to TIGIT (T cell immune receptor with Ig domain and ITIM), an inhibitory checkpoint receptor that plays a critical role in immune regulation. Dargistotug (M-6223) mitigates NK cell depletion, enhances cytokine secretion, modulates effector T cell activity, and increases regulatory T cell (Treg) function, thereby contributing to the broader immunosuppressive environment. Dargistotug (M-6223) has thus become an important agent in research focused on immune checkpoint inhibition.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC683640-100 1x 100 µL
Involucrin (Squamous Cell Terminal Differentiation Marker) (rIVRN/827), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC042550-500 1x 500 µL
NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) (NGFR/2550R), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 