EGFR-IN-90
Product Specifications
Target
EGFR
Related Pathways
JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
EGFR-IN-90 (compound 34), an orally active EGFR inhibitor, demonstrates potent activity against EGFRL858R/T790M/C797S with an IC50 of 5.1 nM and effectively inhibits the proliferation of the H1975-TM cell line carrying EGFRL858R/T790M/C797S mutations with an IC50 of 0.05 ?M. Additionally, EGFR-IN-90 suppresses tumor growth in the H1975-TM xenograft tumor model [1].
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/132882306451898632/T82491
Available Sizes
Curated Selection
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