Estrogen receptor modulator 10
Product Specifications
CAS Number
2991504-90-4
Target
Estrogen Receptor/ERR, Caspase, Bcl-2 Family
Related Pathways
Endocrinology/Hormones, Proteases/Proteasome, Apoptosis
Bioactivity
Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM) . It has the capability to induce apoptosis and block cells at the G1/G0 phase, making it applicable in cancer research [1].
Smiles
C(C(CO)(F)F)N1[C@@H](C2=C(C=3C(N2)=CC=CC3)C[C@H]1C)C4=C(F)C=C(NC5CN(CCCS(CCCC(C(F)(F)F)(F)F)(=O)=O)C5)C=C4F
Molecular Formula
C32H37F9N4O3S
Molecular Weight
728.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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